Japanese Correspondence
Yamada Science Foundation
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Progress Report of YSF Supported Science Program


Summary of Research Projects (Supports in 2003 Fiscal Year)
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Subjects Semi-microscopic scale self-organization of soft condensed matters
Representative researcher Kyoto University Hideki SETO
Joint researcher Hiroshima University Norifumi YAMADA
Kyoto University Mafumi HISHIDA
Kyoto University Tonau NAKAI
Kyoto University Takao OHTA
A characteristic feature of soft condensed matters is its hierarchical structures from microscopic scale (order of angstrom) to macroscopic scale (order of micrometer). Lipid molecules are known to form a bilayer structure with hydrophobic tails inside, and normally, they self-assemble as multi-lamellar structure. However, in biological bodies, they spontaneously aggregate as macroscopic scale liposomes, which is called uni-lamellar vesicles, depending on their functions such as living cells, nucleuses, mitochondrias, and so on. In order to understand the origin of the liposome formation, we investigated structures of lipids and amphiphilic molecules under various conditions by means of small-angle x-ray and neutron scattering, neutron spin echo, optical microscope, and atomic force microscopy. The results indicated that the cooperation of membrane fluctuation and electoronic repulsion or osmotic pressure induces the unbinding transition, i. e., a inter-membrane distance diverges to infinity.